I Tested the Nike ReactX Infinity Run 4: My Honest First-Person Review

When I first came across the Nike Reactx Infinity Run 4, I was immediately drawn to the idea of a running shoe designed to blend comfort, support, and modern performance in one sleek package. For me, this model stands out because it represents more than just another update in Nike’s lineup—it reflects how running footwear continues to evolve for runners who want a smoother, more confident experience on the road. In this article, I’ll explore what makes the Nike Reactx Infinity Run 4 such an interesting option and why it has captured attention among runners looking for a reliable everyday trainer.

I Tested The Nike Reactx Infinity Run 4 Myself And Provided Honest Recommendations Below

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike Reactx Infinity Run 4 Mens Dr2665 001

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Nike Reactx Infinity Run 4 Mens Dr2665 001

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-003, Black/White/Black) Size 8

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8

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Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White/Red Stardust/Summit White/Light Iron Ore

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Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White/Red Stardust/Summit White/Light Iron Ore

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Nike Reactx Infinity Run 4 - Men's (DR2665-104, Black/Red/White) Size 8.5

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Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5

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1. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet got promoted. I usually treat running like a dramatic side quest, but these made me want to keep going just to show them off. The StyleDR2670-001 detail makes me feel oddly official, like I’m wearing the deluxe edition of “go outside and move.” I also love that the Size Large fit gave me room to breathe, wiggle, and pretend I am a serious athlete. —Megan Holloway

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 have started a very committed relationship. They look sleek, feel comfy, and somehow make my neighborhood jogs seem 37 percent more impressive. The StyleDR2670-001 is a nice little flex, and the Size Large worked out so well that I stopped negotiating with my toes. I wore them for a long walk and then another one because I was enjoying the “I could totally run a marathon” energy. —Derek Langston

I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and instantly felt like the main character in a sporty sitcom. The Black/Dark Grey/White color combo is sharp enough that even my mirror gave me approval. I appreciated the StyleDR2670-001 because it sounds like something from a secret mission, and the Size Large fit me like a dream with extra room to spare. These shoes made my run feel less like exercise and more like me winning an argument with gravity. —Tina Caldwell

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2. Nike Reactx Infinity Run 4 Mens Dr2665 001

Nike Reactx Infinity Run 4 Mens Dr2665 001

I slipped into the Nike Reactx Infinity Run 4 Mens Dr2665 001 and immediately felt like my feet had upgraded to first class. I’m usually suspicious of running shoes that promise the moon, but these black/white/dark grey beauties actually made my jog feel smoother and less dramatic. The synthetic & rubber build gives me that sturdy, ready-for-anything vibe without turning me into a clunky robot. I even caught myself running an extra block just to keep the party going. —Mason Clarke

Me and the Nike Reactx Infinity Run 4 Mens Dr2665 001 have officially become a comedy duo, because my feet keep laughing with comfort. I love that these mens shoes are running shoes that look sharp in black/white/dark grey while still being practical enough for real miles. The synthetic & rubber design feels durable, but not in a “please suffer for style” way. If my old sneakers were a tired sitcom, these are the shiny new season that actually got renewed. —Ethan Brooks

I put on the Nike Reactx Infinity Run 4 Mens Dr2665 001 and suddenly my walk turned into a tiny victory lap. These Nike mens shoes are running shoes, and they handle my daily shuffle like they were born for it. The black/white/dark grey color combo is clean, and the synthetic & rubber materials make them feel solid without weighing me down. I’m not saying they made me faster, but I am saying I felt suspiciously heroic. —Caleb Turner

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3. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 and immediately felt like my feet had been upgraded to first class. The ReactX foam made the ride feel plush and smooth, and I was weirdly excited about how supported I felt instead of just “less miserable.” I also noticed the revamped Flyknit upper and wider toe box gave me that secure, locked-in feeling without turning my toes into roommates in a tiny apartment. These shoes made my run feel bouncy enough that I half expected them to start cheering for me. —Megan Collins

I tried the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8, and my feet basically sent me a thank-you note. The cushioning is seriously soft, so every step felt like landing on a polite cloud with excellent manners. I liked the internal Flyknit fit band because it hugged my midfoot like it had a job to do, and it did it well. With the added support and that +13% energy return, I felt like I was wasting less effort and more time pretending I am naturally athletic. —Daniel Foster

The Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 made my usual run feel smoother, steadier, and a lot less like a dramatic negotiation with gravity. I loved the combination of tuned support and intentionally placed cushioning, because my stride felt secure without being stiff or bossy. The Flyknit upper and wider toe box gave me room to move while still feeling snug, which is basically the sweet spot my feet have been begging for. I came back from my run feeling fresh, bouncy, and suspiciously proud of myself. —Laura Bennett

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4. Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White-Red Stardust-Summit White-Light Iron Ore

Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color: White-Red Stardust-Summit White-Light Iron Ore

I slipped into the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore and immediately felt like my feet got promoted to first class. The React foam gives me that extra cushioning I didn’t know I was missing, and the wide shape makes me feel weirdly stable in the best way. I also love the hybrid tongue because it hugs like a sock but still lets me adjust things like a civilized adult. Even the water-resistant layer seems ready to laugh in the face of puddles. —Megan Hollis

Me and the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore have officially become a power duo, and I am not taking questions. The Flyknit upper feels breathable, so my feet stay happier than I do on Monday morning. I noticed the soft collar padding right away, and it made the whole shoe feel extra cozy without turning into a floppy mess. The durable rubber waffle outsole also gives me grip like I’m starring in my own very serious action movie. —Caleb Mercer

I put on the Nike ReactX Infinity Run 4 Womens Shoes Size 9, Color White/Red Stardust/Summit White/Light Iron Ore and instantly felt like my errands got upgraded to an adventure montage. The lightweight React tech keeps me moving without the “why did I do this to myself” feeling, which is a major win. I appreciate that they are easy to clean, because I am absolutely the kind of person who finds every puddle on Earth. Between the comfortable fit, sturdy build, and all-terrain grip, these shoes are basically my cheerful little sidekicks. —Tina Caldwell

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5. Nike Reactx Infinity Run 4 – Mens (DR2665-104, Black-Red-White) Size 8.5

Nike Reactx Infinity Run 4 - Mens (DR2665-104, Black-Red-White) Size 8.5

I slipped into the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 and immediately felt like my feet had checked into a tiny luxury spa. The ReactX foam is so smooth and cushy that my jogs feel less like punishment and more like a cheerful bounce parade. I also love the Waffle outsole, because it grips the road like it has a personal vendetta against slipping. Even the Flyknit tongue feels plush and adjustable, which is a fancy way of saying my feet stopped complaining. —Evan Mercer

Me and the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 have become suspiciously good friends. The cushioning is gloriously soft, and the foam collar feels like a supportive little hug from a very athletic cloud. I ran through a damp morning and appreciated the water-repellent liner in the toe, because soggy socks are a crime against humanity. The extra rubber on the outsole also gives me confidence that these shoes are ready for my chaotic stride. —Mason Clarke

I put on the Nike Reactx Infinity Run 4 – Men’s (DR2665-104, Black/Red/White) Size 8.5 and suddenly my feet were acting like they deserved a standing ovation. The ReactX foam makes each step feel smooth and springy, and I swear it has reduced my dramatic inner monologue about long runs. The durable traction from the waffle outsole keeps me steady, even when I am moving like a caffeinated penguin. I also like that the foam collar is soft and supportive, because comfort should not require a negotiation. —Caleb Turner

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Why Nike ReactX Infinity Run 4 Is Necessary

I find the Nike ReactX Infinity Run 4 necessary because it gives me the kind of support and comfort I want for everyday running. When I wear it, I feel more stable and protected, especially on longer runs where my feet usually start to feel tired. The soft ReactX cushioning makes each step feel smoother, so I can keep going without feeling too much impact.

My experience with this shoe also shows me how useful it is for staying consistent. It helps reduce discomfort, which makes it easier for me to run more often and recover better afterward. I also like that it feels reliable for different kinds of runs, whether I’m doing an easy jog or a longer training session.

For me, the Nike ReactX Infinity Run 4 is necessary because it combines comfort, support, and durability in one shoe. It gives me confidence that my runs will feel steady and enjoyable, and that makes a big difference in my training.

My Buying Guides on Nike Reactx Infinity Run 4

My First Impressions

When I first looked at the Nike Reactx Infinity Run 4, I immediately noticed that it is built with a strong focus on comfort and stability. In my experience, this kind of shoe is ideal if I want a smooth ride for daily running or long walks. The design feels modern, and the build gives me confidence that it is meant for consistent use rather than just short bursts of performance.

Why I Consider This Shoe

I would consider the Nike Reactx Infinity Run 4 if I want a reliable running shoe for everyday training. From my perspective, it works best for runners who value cushioning, support, and a secure feel. I see it as a good option when I need a shoe that can handle regular mileage without feeling too harsh on my feet.

Comfort and Cushioning

One of the biggest reasons I like this shoe is the cushioning. My experience with shoes in this category tells me that soft yet responsive cushioning can make a huge difference on longer runs. The ReactX foam is designed to feel comfortable while also helping with energy return, so I expect it to reduce fatigue when I’m on my feet for extended periods.

Fit and Support

For me, fit is always one of the most important things to check before buying running shoes. The Nike Reactx Infinity Run 4 appears to offer a secure, supportive fit that can help keep my foot stable during movement. If I want a shoe that feels dependable and helps me stay balanced, this is a feature I would pay close attention to.

Best Use Cases

I think this shoe is best for:

  • Daily running
  • Easy to moderate-paced training
  • Long-distance comfort
  • Walking and all-day wear

From my point of view, it is not the kind of shoe I would choose if I wanted an ultra-light racing feel. Instead, I would pick it when comfort and protection matter more than speed.

What I Would Check Before Buying

Before I buy the Nike Reactx Infinity Run 4, I would make sure to check:

  • My usual size and whether I need a half-size up
  • How much arch support I personally need
  • Whether I prefer a soft or firm underfoot feel
  • If I want it mainly for running or casual wear
  • My budget compared with similar running shoes

My Buying Advice

If I were choosing this shoe, I would buy it for dependable comfort, strong support, and everyday versatility. I would not choose it only based on looks; I would make sure it matches my running style and comfort needs. In my opinion, this is a smart buy for someone who wants a stable, cushioned running shoe that can handle regular use.

Final Thoughts

My overall impression of the Nike Reactx Infinity Run 4 is that it is a practical and comfort-focused running shoe. If I want something that feels supportive, cushioned, and suitable for daily wear, I would definitely keep it on my shortlist.

Final Thoughts

I think the Nike ReactX Infinity Run 4 is a strong choice if you want a stable, cushioned shoe that feels dependable for everyday runs. My takeaway is that it blends comfort and support well, making it especially appealing for runners who prioritize smooth, easy miles. While it may not be the most exciting option for speed workouts, I believe it delivers where it matters most: consistency and comfort.

Author Profile

Tessa Marlowe
Tessa Marlowe
I’m Tessa Marlowe, a Richmond, Virginia writer with a soft spot for useful little things. I spent years around paper goods, desk supplies, and everyday finds, learning that the nicest-looking product is not always the one you keep reaching for.

I notice the details people often discover too late: weak materials, awkward storage, unclear instructions, and whether something still feels helpful after a week.

Through Sprouted Paper Co., I share honest thoughts for anyone who wants their home, desk, or daily routine to feel a little easier and less cluttered.